Barry McCarthy and Boyd Rankin have been ruled out of the Ireland squad for the second ODI against England with their places taken by Peter Chase and George Dockrell.
McCarthy pulled up after just five balls of the England innings and an MRI scan this morning revealed a muscle tear at the back of his knee.
Rankin didn't play on Thursday and has been troubled by an ongoing back injury in recent weeks.
Mark Adair would have been the obvious like-for-like replacement for McCarthy, but his ankle troubles mean the selectors opted for Leinster left-arm spinner George Dockrell and Malahide paceman Peter Chase.
"Barry McCarthy is unfortunately out of the next two ODIs after this morning’s MRI revealed a tear in a muscle at the back of his knee, while Boyd Rankin has been taken out of the 14 for tomorrow’s game as he manages a flare-up of an old back injury," said Head of Selectors Andrew White.
“Coming into the 14 as a direct like-for-like replacement for Boyd is Peter Chase. Peter has been bowling really well in the nets, having made adjustments to his run-up over last 6 months, and has impressed coaches. George Dockrell completes the 14 given the all-round game we know he offers.”
White paid tribute to debutant Curtis Campher who impressed with an unbeaten half century and a wicket.
“The Selectors are, of course, delighted with Curtis Campher’s debut – his positive play, composure under pressure and energy with the ball was very pleasing to see – to be making your debut against the world champions was highly pressurised, so for him to respond so well is a credit to his temperament and confidence to play at this level.”