Five wickets apiece for Gary Kidd and Haseeb Azam saw Waringstown dismiss Holywood for just 53 in their rearranged Gallagher Senior Cup tie at Seapark.
Former Irish international Kidd took 5 for 9 to pip overseas professional Azam to the Man-of-the-Match accolade.
Holywood had no answer to the pair, with only Tom Anderson (17) and Adam Gardner (13) reaching double figures as they were skittled inside just 17.1 overs.
The Waringtown chase saw Holywood take three wickets, two for Kyle Walsh and one for Jack Chrishop, but it was all over very quickly as the seven wicket victory took just 11 overs.
Waringstown now face Instonians in the quarter-finals at The Lawn on Saturday.